000058352 001__ 58352
000058352 005__ 20161222124805.0
000058352 0247_ $$2doi$$a10.2174/1570179412666150914200035
000058352 0248_ $$2sideral$$a97064
000058352 037__ $$aART-2016-97064
000058352 041__ $$aeng
000058352 100__ $$0(orcid)0000-0001-7773-9418$$aMatute Najarro, Rosa Pilar$$uUniversidad de Zaragoza
000058352 245__ $$aRecent advances in the preparation of enantiomerically pure hydroxylamines from nitrones
000058352 260__ $$c2016
000058352 5060_ $$aAccess copy available to the general public$$fUnrestricted
000058352 5203_ $$aThis review covers the recent advances in the synthesis of enantiomerically pure hydroxylamine’s employing nitrones as starting materials. Nucleophilic additions of organometallic reagents to nitrones are the most common way for introducing a hydroxyamino group into carbon skeletons with the concomitant formation of a new carbon-carbon bond. Addition of nucleophiles derived from enolates, cyanide or fluorinated derivatives allows the preparation of complex structures. Radical additions and, in particular samarium diiodidemediated reductive coupling of nitrones with carbonyl compounds and a, ß-unsaturated esters have also been considered. All these approaches provide efficient methods of preparation of enantiomerically pure hydroxylamine’s that are valuable synthetic intermediates.
000058352 536__ $$9info:eu-repo/grantAgreement/ES/DGA/E10$$9info:eu-repo/grantAgreement/ES/MICINN/CTQ2013-44367-C2-1-P
000058352 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000058352 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000058352 700__ $$aGarcía Viñuales, Sara
000058352 700__ $$aHayes, H.
000058352 700__ $$0(orcid)0000-0002-2855-4801$$aGhirardello , Mattia$$uUniversidad de Zaragoza
000058352 700__ $$aDarù, A.
000058352 700__ $$0(orcid)0000-0003-3433-6701$$aTejero López, Tomás$$uUniversidad de Zaragoza
000058352 700__ $$0(orcid)0000-0001-8355-2289$$aDelso Hernández, José Ignacio$$uUniversidad de Zaragoza
000058352 700__ $$0(orcid)0000-0002-2202-3460$$aMerino Filella, Pedro$$uUniversidad de Zaragoza
000058352 7102_ $$15005$$2790$$aUniversidad de Zaragoza$$bDepartamento de Ingeniería Química y Tecnologías del Medio Ambiente$$cTecnologías del Medio Ambiente
000058352 7102_ $$12013$$2765$$aUniversidad de Zaragoza$$bDepartamento de Química Orgánica$$cQuímica Orgánica
000058352 773__ $$g13, 5 (2016), 669-686$$pCurr. Org. Synth.$$tCURRENT ORGANIC SYNTHESIS$$x1570-1794
000058352 8564_ $$s654293$$uhttp://zaguan.unizar.es/record/58352/files/texto_completo.pdf$$yPostprint
000058352 8564_ $$s48822$$uhttp://zaguan.unizar.es/record/58352/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000058352 909CO $$ooai:zaguan.unizar.es:58352$$particulos$$pdriver
000058352 951__ $$a2016-12-21-12:49:00
000058352 980__ $$aARTICLE