000057867 001__ 57867
000057867 005__ 20161215123621.0
000057867 0247_ $$2doi$$a10.1371/journal.pone.0093491
000057867 0248_ $$2sideral$$a88231
000057867 037__ $$aART-2014-88231
000057867 041__ $$aeng
000057867 100__ $$aMuniesa, Ana
000057867 245__ $$aEstimation of the relative sensitivity of qpcr analysis using pooled samples
000057867 260__ $$c2014
000057867 5060_ $$aAccess copy available to the general public$$fUnrestricted
000057867 5203_ $$aThe high sensitivity of qPCR makes it a desirable diagnostic method in epidemiological surveillance programs. However, due to high costs, the use of pooling has been suggested. In this paper, an algorithm based on the Montecarlo method has been designed and implemented. The algorithm had been tested in many different situations, and finally it was validated with a real dataset. Moreover, based on the results obtained and depending on pooling conditions, a drastic decrease of sensitivity is observed.
000057867 536__ $$9info:eu-repo/grantAgreement/ES/MICINN/MTM2010-21037
000057867 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000057867 590__ $$a3.234$$b2014
000057867 591__ $$aMULTIDISCIPLINARY SCIENCES$$b8 / 56 = 0.143$$c2014$$dQ1$$eT1
000057867 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000057867 700__ $$0(orcid)0000-0002-3698-6719$$aFerreira González, Chelo$$uUniversidad de Zaragoza
000057867 700__ $$aFuertes, Héctor
000057867 700__ $$aNalaihel, Nabil
000057867 700__ $$ade Blas, Ignacio
000057867 7102_ $$12005$$2595$$aUniversidad de Zaragoza$$bDepartamento de Matemática Aplicada$$cMatemática Aplicada
000057867 773__ $$g9, 4 (2014), e93491 [5 pp]$$pPLoS One$$tPLoS One$$x1932-6203
000057867 8564_ $$s607047$$uhttp://zaguan.unizar.es/record/57867/files/texto_completo.pdf$$yVersión publicada
000057867 8564_ $$s119590$$uhttp://zaguan.unizar.es/record/57867/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000057867 909CO $$ooai:zaguan.unizar.es:57867$$particulos$$pdriver
000057867 951__ $$a2016-12-14-14:52:13
000057867 980__ $$aARTICLE